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Job Description

Onsite in Boston, BioNTech offers an opportunity to lead data engineering at the intersection of science and medicine. In this Associate Director Data, Digital & Informatics (Senior Data Engineer) role, you will design, deliver, and maintain scalable, enterprise-grade data pipelines on Spark, Databricks, Delta Lake, and AWS to support analytical, scientific, clinical, and operational decision making across the R&D lifecycle. The position carries a competitive salary range of USD 146,300 - 234,100 per yearly and provides a path to influence platform strategy, governance, and collaboration across cross-functional teams. You will mentor engineers, partner with Platform, Cloud, and DevOps teams, and work with CROs and external vendors to advance data capabilities in a regulated, data-driven environment.

Responsibilities

  • Design, build, maintain, and optimize scalable, secure, and resilient data pipelines using Spark, Databricks, Delta Lake, and AWS.
  • Coordinate data flow across clinical systems (EDC, CTMS, IRT, Rave, biosample systems, BRIMS, PV, MDM) and implement transformations aligned to CDISC standards (CDASH, ODM, SDTM, ADaM).
  • Establish data quality, testing, monitoring, and performance frameworks; perform clinical data cleaning, reconciliation, validation, and QC.
  • Collaborate with Platform, Cloud, and DevOps teams to evolve the clinical data platform; own CI/CD automation, infrastructure-as-code, observability, data lineage, and pipeline monitoring.
  • Lead cross-functional data engineering programs as a senior engineering leader; mentor engineers on best practices, coding standards, automation, and reproducibility.
  • Integrate data across R&D domains including translational science, clinical development, safety, regulatory, and real-world evidence, with API-based ingestion (REST, GraphQL) and metadata management.
  • Collaborate with QA, Data Analysts, Data Scientists, Cloud Ops, Biostatistics, Clinical Ops, CROs, and external vendors to foster an open, inclusive team culture.
  • Engage governance, compliance, and security to ensure alignment with GxP, CSV, FAIR, privacy, and data ethics.
  • Build and maintain data models, specifications, mapping documents, and QC documentation, contributing to enterprise data strategies and architecture roadmaps.

Requirements

  • Bachelor’s or Master’s degree in computer science, engineering, a related field, or equivalent practical experience.
  • 6 to 10+ years of data engineering experience with production-grade data pipelines and large-scale distributed systems.
  • 2 to 6+ years of experience with Databricks and AWS, plus ETL/ELT tools and cloud data lake/warehouse solutions.
  • Experience in biotech/pharma regulated or complex scientific environments, including GxP/CSV and data governance (privacy, data ethics).
  • Strong SQL, PySpark, and Python skills; proficiency with SAS and R; experience with CI/CD, DevOps (GitHub), infra-automation (Terraform), data modeling, metadata management, and data quality frameworks.
  • Hands-ons experience with clinical data standards and systems (CDISC, EDC, CTMS, IRT, Rave, biosample systems, BRIMS, PV, MDM) and data masking/blinded-unblinded workflows.
  • Familiarity with ML/AI workloads and model-ready data engineering; experience across translational science, clinical development, safety, regulatory, and real-world evidence domains.
  • Experience working with CROs and external vendors; strong analytical, problem-solving, communication, and cross-functional partnership skills.
  • A customer-oriented and agile mindset, with the ability to manage competing priorities and to work effectively with people from diverse disciplines, cultures, and backgrounds.

Technologies

  • Spark, Databricks, Delta Lake, AWS
  • REST, GraphQL
  • GitHub, Terraform
  • SAS, R, Python, PySpark, SQL
  • Rave, CTMS, EDC, IRT, BRIMS, PV, MDM

How to apply

Apply now by submitting your documents through our online form. Include your Curriculum Vitae, a copy of your ID, copies of degree certificates and professional certificates, a motivation letter, and your contact details.

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