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Job Description

Axle in Frederick, MD (onsite) is seeking a Bioinformatics/Data Scientist to analyze multi-omics data from organoid systems and normal tissues, supporting the NIH SOM Center with a salary range of USD 105,000 - 120,000 per year.

Responsibilities

  • Analyze complex datasets including single-cell RNA sequencing, bulk RNA sequencing, proteomics, and metabolomics from organoid systems and their tissue counterparts.
  • Develop and implement computational pipelines for data processing, quality control, and statistical analysis.
  • Integrate SOM generated data with publicly available datasets to benchmark organoid characteristics against normal tissue profiles.
  • Collaborate with experimental teams to interpret results, guide protocol optimization, and contribute to manuscript preparation and presenting findings at scientific conferences.

Requirements

  • PhD in bioinformatics, computational biology, biostatistics, or a related quantitative field.
  • Extensive experience with single-cell data analysis, including familiarity with Seurat, Scanpy, or similar platforms.
  • Strong programming skills in R and Python, with experience in statistical analysis and data visualization.
  • Knowledge of proteomics and metabolomics data analysis workflows.

Technologies

  • Seurat
  • Scanpy
  • R
  • Python

Benefits

  • Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts: Healthcare (FSA)
  • Flexible Spending Accounts: Parking Reimbursement Account (PRK)
  • Flexible Spending Accounts: Dependent Care Assistant Program (DCAP)
  • Flexible Spending Accounts: Transportation Reimbursement Account (TRN)

Cover Letter Required

Please answer the following questions and submit application at: BIOINFORMATICS/DATA SCIENTIST:

  • What experience do you have working with large datasets and compute clusters?
  • Describe your experience building workflows/pipelines and/or using bioinformatics software and tools to analyze data.
  • What programming languages are you comfortable using for bioinformatics data analysis?
  • What bioinformatics areas are you familiar with? (e.g., single cell, bulk genomics, transcriptomics, epigenetics, flow, spatial, metagenomics, etc.)
  • What life science disciplines do you have experience in? (e.g., immunology, infectious disease, cancer research, etc.)
  • Provide examples of basic machine learning/AI concepts and/or how you've applied them in bioinformatics data analysis.

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