Bioinformatics / Data Scientist

Axle is seeking a Bioinformatics / Data Scientist to help advance multi-omics analysis for organoid systems and corresponding normal tissues. This onsite role in Rockville, MD combines deep computational work with close collaboration across experimental teams, with a focus on organoid fidelity characterization, biomarker discovery for successful differentiation, and the development of computational quality assessment frameworks.

Compensation: USD 105,000 - 120,000 per year.

What you’ll do

• Analyze complex multi-omics datasets, including single-cell RNA sequencing, bulk RNA sequencing, proteomics, and metabolomics from organoid systems and their tissue counterparts.
• Partner with experimental wet-lab teams to refine experimental design and optimize protocols for both knowledge discovery and performance.
• Build and run computational pipelines for data processing, quality control, and statistical analysis.
• Integrate SOM-generated data with publicly available datasets to benchmark organoid characteristics against normal tissue profiles.
• Collaborate with experimental teams to interpret results and support protocol optimization.
• Contribute to manuscript preparation and present findings at scientific conferences.

What you bring

• PhD in bioinformatics, computational biology, biostatistics, or a related quantitative field.
• Extensive experience with single-cell data analysis, including familiarity with Seurat, Scanpy, or comparable platforms.
• Strong programming proficiency in R and Python, plus experience with statistical analysis and data visualization.
• Basic knowledge of proteomics and metabolomics data.

Preferred background

• Prior experience analyzing organoid datasets.
• Experience with machine learning approaches for biological data, familiarity with pathway analysis tools, and knowledge of developmental biology principles.
• Experience working in high-performance computing environments and using version control systems.

Tools you’ll use

• R, Python, Seurat, Scanpy

Benefits

• 100% Medical, Dental & Vision Coverage for Employees
• Paid Time Off and Paid Holidays
• 401K match up to 5%
• Educational Benefits for Career Growth
• Employee Referral Bonus
• Flexible Spending Accounts: Healthcare (FSA)
• Parking Reimbursement Account (PRK)
• Dependent Care Assistant Program (DCAP)
• Transportation Reimbursement Account (TRN)